Postdoctoral Fellow – Immunology and Single-Cell Genomics in T1D @ University of Pennsylvania

We are seeking a highly motivated postdoctoral scientist with expertise in both computational biology and experimental immunology to join our team in Philadelphia. Our lab is investigating the mechanisms underlying autoimmunity in type 1 diabetes (T1D) and identifying novel cellular biomarkers for early disease detection. You will have the opportunity to work with unique, well-characterized human samples and to collaborate with leaders in immunology and translational research.

Key Responsibilities:

• Define T cell responses to commensal microbes in intestinal tissues and peripheral blood using ex vivo stimulation and MHC class II tetramer-based approaches.
• Perform and analyze single-cell RNA-seq, ATAC-seq, and TCR-seq from sorted antigen-specific T cells and various other immune subsets.
• Identify and validate novel cellular biomarkers of islet autoimmunity and explore their mechanistic roles in disease pathogenesis.

Qualifications:

• Ph.D. in immunology, computational biology, systems biology, or a related field
• Experience with single-cell genomics, flow cytometry, and T cell biology
• Strong computational skills in R or Python, with a track record of analyzing high-dimensional datasets
• Excellent communication, organization, and teamwork skills

Benefits:

• Competitive salary and benefits package.
• Access to cutting-edge research facilities, unique human tissues from organ donors, clinical trial samples, and resources at the University of Pennsylvania.
• Mentorship and opportunities for career development and advancement.
• Vibrant research environment with a supportive and inclusive community.

For more information, please see the following link: https://sites.google.com/view/su-lab/home

To apply, please submit your CV and a cover letter outlining your research interests to Dr. Laura Su (laurasu@upenn.edu). We look forward to welcoming you to our team!