Bioinformatics III @ Goldbelt, Incorporated

July 22, 2021


Goldbelt C6, LLC is seeking a Bioinformatics III to support the Surveillance Branch. This opportunity is in the Division of Healthcare Quality Promotion (DHQP) of the National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).  



  • Maintain, de-bug, execute and improve bioinformatics tools and pipelines used in-house, including implementation of workflow manager programs (e.g., nextflow)
  • Build new bioinformatics tools and pipelines as appropriate, including creating containers for applications (e.g., docker, singularity)
  • Maintain updated git account documenting scripts and programs. 
  • Analyze sequence data from scientific projects and programs of bacterial isolates using appropriate programs and bioinformatics tools and pipelines, including:
    • Quality assessment of next generation sequence data 
    • Analyses for identification and subtyping of healthcare-associated and emerging bacterial pathogens
  • Identify, validate, and implement methods and procedures to analyze next generation sequencing data, including methods for characterization and phylogenetic analyses and adjustments in methods and procedures as appropriate.
  • Coordinate sequence data sharing with requestors and collaborating laboratories.
  • Manage incoming sequence data for processing, documentation, tracking, and inventory as needed.
  • Integrate laboratory (conventional and next generation), clinical, and epidemiologic data generated to provide analyses of data from healthcare-associated infection and other emerging pathogen studies and investigation. 
  • Upload sequence data (raw reads and/or assemblies, as appropriate) to public databases (e.g., NCBI) under timelines established by the SME/project leads or Team Leads.
  • Develop new and improved concepts, principles, and techniques that will advance the body of knowledge of information management.
  • Apply advanced computer science methods and techniques to solve complex computer processing requirements for data analysis, inventory management and clinical system interface.
  • Enhance existing data systems; edit, proofread, and critique team members in a professional manner.



  • Highly proficient or possess extensive experience with Bash (no exceptions)
  • Highly proficient or possess extensive with Python (no exceptions)
  • Must be proficient with common bioinformatics open-source tools (e.g., samtools, bcftools, bwa-mem), HPC (high performance computing), and NCBI.
  • Proficient with tools to elucidate mobile genetic elements from short read data (e.g., PlasFlow). 
  • Self-motivated with a strong attention to detail and accuracy.
  • Fluent English in written, verbal, and interpersonal exchanges.



  • Bachelor’s degree in Biostatistics, Statistics, Epidemiology, Public Health, or related field.
  • 3 – 8 years’ relevant experience in a Bioinformatics role.



  • Master’s degree in Biostatistics, Statistics, Epidemiology, Public Health, or related field.
  • Experience with Oxford Nanopore technology (e.g., MinION) platform bioinformatics analyses.
  • Experience with nextflow or other workflow manager programs, creating containers for applications (e.g., docker, singularity), Git (i.e., GitLab, GitHub), frameworks for storing and processing large data sets (e.g., Hadoop).
  • Experience with tools to elucidate mobile genetic elements from short read data (e.g., PlasFlow).
  • Cloud migration and integration is a huge plus.

Read more and apply here.