Vector Engineering Scientist @ Ring Theraputics

November 12, 2020

Company Summary: 

Ring Therapeutics Inc. is a privately held, early-stage biotechnology company pioneering a completely novel form of gene therapy  by exploiting a family of naturally occurring commensal viruses to create the first re-dosable and targetable DNA medicines. This  approach enables a powerful new class of tropic, persistent, non-integrating vectors that overcome the immunogenicity, and  limited tropism of existing gene therapy vectors. Ring Therapeutics is leveraging this versatile technology to develop a broad  pipeline of novel, targeted medicines for disease with high unmet medical need. 

Ring Therapeutics was founded by Flagship Pioneering, focused on launching breakthrough companies based on internally  conceived innovations and insights. Flagship Pioneering has created over 40 groundbreaking companies over the past fifteen  years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in  human health and sustainability. These companies include Moderna (MRNA), Seres Therapeutics (NASDAQ:MCRB), Syros  Pharmaceuticals (SYRS), Rubius Therapeutics (RUBY), Axcella Health, Evelo Biosciences (EVLO), and Indigo Agriculture. 

Position Summary: 

Ring Therapeutics is seeking a viral vector engineering scientist to join the Platform and Biology team to help develop new DNA  medicine technologies. The candidate will help design, build, characterize, and optimize engineered viral vectors. The candidate  will design experiments, perform experiments, analyze and present data. The candidate will interface with equipment companies,  research institutes/universities, and contract manufacturing organizations as required to accelerate the development effort. This  will be a great opportunity to participate in cutting-edge virology, viral genome engineering, and synthetic biology research. We are  searching for enthusiastic and highly motivated individuals who are comfortable multitasking and working both with a team and independently on various aspects of the viral platform development. 

Key Responsibilities: 

• Design, make, and characterize new viral vectors 

• Supervise research associates supporting key research objectives 

• Maintain lab notebooks, and report results to the scientific team 

Minimum Qualifications: 

• Ph.D. in virology and viral vectors. 

• 2 years of postdoctoral experience, in academic, pharmaceutical, or biotechnology settings. 

• Experience with 

o design and characterization of viral vectors, particularly for gene therapy applications 

o classical virology techniques including virus culture, isolation (e.g., via centrifugation methods, including isopycnic),  and quantification (infectivity, transduction assays, plaque assays, TCID, etc…) 

o molecular biology and recombinant DNA techniques, including transfections of mammalian cells. • Demonstrated ability to work with highly skilled teams in a fast-paced, entrepreneurial and technical environment. • Excellent communication and presentation skills, capable of conveying technical information in a clear and thorough  manner. 

• Comfortable delivering against challenging commitments. 

• Confident, execution focused, team oriented, with an ability to thrive in an entrepreneurial environment. 

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from  any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless  contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will  automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. 

To apply: Follow the link below, or go to: