#  Research Scientist @ The Sharpe Lab at Harvard Medical School 

 





January 30, 2024

 

 

 **The Sharpe Lab at Harvard Medical School has created the CHIME (CHimeric IMmune Editing) system for using CRISPR-based in vivo screening to discover novel cancer immunotherapy targets. This project is performed by a multidisciplinary team of research scientists and research associates who conduct in vivo screens in preclinical murine cancer models, validation/mechanism studies, and technology development centered on in vivo perturbation of immune cells. The overall aim of this project to improve our understanding of mechanisms of T-cell mediated tumor immunity.**

 **We seek a motivated, experienced, and creative immunologist to join our team as a Research Scientist and lead a self-directed project that interfaces with these aims. The candidate will pursue his/her own project within the group supervising existing research associates working on this project. The candidate will also be responsible for leading manuscript writing on their projects. Candidates must have a strong background in immunology and cancer biology research, with experience in animal models required.**

 **The ideal candidate will also possess superior experimental planning, organizational, and execution skills; an open mind; the ability to mentor and manage research associates; a strong desire to collaborate and develop new technologies; and a proven ability to efficiently and effectively solve problems.**

 **Harvard Medical School offers an outstanding working environment. The workplace culture is exciting, collaborative, and supports a healthy work-life balance. Harvard offers a comprehensive benefits package: [https://hr.hms.harvard.edu/working-hms/benefits&nbsp](https://hr.hms.harvard.edu/working-hms/benefits&nbsp);**

 **Principal Duties and Responsibilities**

 **• Develop, lead, and execute research projects independently**

 **• Lead manuscript writing on their project**

 **• Serve as the primary mentor of research associates working on their project • Stay up-to-date on literature and think creatively and critically about the project • Contribute to the lab through teamwork and discussion**

 **• Attend high-level meetings and report progress to funding partners through presentations and progress reports**

 **• Present research internally at Harvard and externally at scientific meetings**

 **Minimum Qualifications**

 **PhD in relevant field (immunology, cancer biology, or similar)**

 **Extensive experience with tumor immunology preclinical models**

 **Demonstrated scientific contributions to the field with at least 1 first-author paper Applicants should send CV to Martin LaFleur at [martin\_lafleur@hms.harvard.edu](mailto:martin_lafleur@hms.harvard.edu)**



 

 

 



 

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