Post-doctoral fellow positions – Harrison Lab – Benaroya Research Institute

The Harrison Lab at the Benaroya Research Institute (BRI) in Seattle, WA is seeking highly-motivated postdoctoral candidates for projects in mucosal immunology, specifically induction and regulation of commensal-, and helminth-specific T and B cell responses in the skin and gastrointestinal tract.

The Harrison Lab (www.harrison-lab.org) works to understand the mechanisms controlling host-microbe interactions at barrier sites such as the skin and gastrointestinal tract. We study how our resident commensal microbes influence the development, education and function of our immune system. To do so, we utilize a multi-disciplinary approach combining development and implementation of tools to track commensal-specific T and B cells in healthy and inflamed tissues, with single-cell and population level transcriptomics and epigenetic analyses of T and B cell differentiation to investigate how the host mounts and regulates immunity to the microbiome.

Potential projects in the Harrison Lab will build on exciting recent findings including:

• The transcriptional and epigenetic basis of commensal-specific T cell differentiation during healthy

  immune responses and immune-mediated diseases.

• Post-transcriptional regulation of tissue-resident T cell function.

• Induction and regulation of commensal-specific B cells in the gastrointestinal tract.

• Helminth-specific immunity in the gastrointestinal tract.

  A recent, or anticipated, PhD in Immunology is required. Experience in multi-parameter flow-cytometry is strongly preferred, as is experience with animal handling and models of inflammation/infection.

  Interested candidates should send inquiries, including a 1-page description of their current work, and a C.V., to oharrison@benaroyaresearch.org

  All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, citizenship, disability or protected veteran status.

  Benaroya Research Institute at Virginia Mason

  1201 Ninth Avenue, Seattle, WA 98101 p 206.342.6500 f 206.342.6580 BenaroyaResearch.org

Benaroya Research Institute is an internationally recognized medical research institute focused on finding cures for autoimmune and immune-mediated diseases. We stress excellence in advanced laboratory experimentation and carefully designed translational research programs. This offers our scientists the opportunity to directly impact the lives of people suffering from diseases including type 1 diabetes, rheumatoid arthritis, multiple sclerosis, allergies and asthma.