Director of Biomarker & Discovery Research @ University of California San Francisco Diabetes Center

November 9, 2021

The Director of Biomarker & Discovery Research (BDR) is a full-time position that is an integral part of the ITN management team related to biomarker discovery and validation efforts associated with multiple complex clinical trials to induce and maintain immunological tolerance.

As Director of BDR the incumbent will be responsible for managing a staff of PhD scientists, designing and developing mechanism of action (MOA) studies for clinical trials, analyzing and interpreting data generated from MOA studies, collaborating on efforts for assay design, development and data interpretation with ITN Principal Investigators and Core Laboratory Directors, and writing and co-writing original research manuscripts for publication submission.

Under the direction of the ITN Deputy Director (UCSF), the incumbent will be responsible for coordinating the design of research projects as they relate to support of ITN clinical trials, including identification of new technologies for consideration by ITN leadership, as well a use of existing assays and providing cost assessments for projects. Oversight of the incumbent's responsibilities will be provided by the ITN Deputy Directors and the ITN Director. Specific goals and deliverables, such as protocols developed, manuscripts written, assay projects completed and overall assessment of the incumbent contributions to the scientific design, development and analysis of the biomarker discovery efforts are the primary basis for evaluation. Additionally, the incumbent s management skills including timeline management, personnel management, communication skills and ability to design, develop and manage complex scientific discovery efforts are essential aspects of successful job performance.

This PhD position requires independent scientific and critical thinking skills with a strong background in immunology and translational medicine in autoimmunity. This position involves communication with professionals in other parts of the ITN, including protocol development and data discussions with the Clinical Trials Group (CTG), discussions of budgets with the ITN Administrative Director (ITN AD), discussions of specimen acquisition, management, shipment, and tracking with the ITN Mechanistic Operations group, and discussions of data base issues with the ITN Bioinformatics (BiG) group. The Director will also be expected to liaise with ITN Principal Investigators (PI s), industry representatives and the ITN Deputy Directors and ITN Director.

Required Qualifications

  • PhD and/or MD with 7-10 years relevant laboratory and management experience focused on human immunology is required.

  • Experience with cell biology, flow cytometry, ELISA, ELISpot, multi-plex immunoassays, proliferation and cytotoxicity assays, and PCR-based technologies is needed.

  • Strong written and oral communication skills are required for writing protocols, detailed scientific documents, and original manuscripts for publication and for giving presentations to scientific and non-scientific professional in a wide variety of meetings.

  • Strong analytical skills are necessary for data analysis and interpretation.

  • Demonstrated experience in managing a research program is required.

  • The candidate should be an independent thinker with demonstrated experience in publications and presentations for the broader scientific community.

Please apply online at

Application Requirements

Document requirements:

  • Curriculum Vitae - CV must clearly list current and/or pending qualifications (e.g. board eligibility/certification, medical licensure, etc.).

  • Cover Letter (Optional)

  • Statement of Research

  • Statement of Teaching (Optional)

  • Statement of Contributions to Diversity - Please see the following page for more details:

  • Misc / Additional (Optional)

Reference requirements:

  • 5 required (contact information only)

Campus Information

All UCSF employees must participate in the UC COVID-19 Vaccination Program. Relevant policy information, FAQ’s, and forms may be found by visiting:

UC San Francisco seeks candidates whose experience, teaching, research, or community service that has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

Job Location

San Francisco, CA